. >>> it has been a deadly holiday weekend on northern california roads. tonight investigators are looking into a horrific crash that killed four people, including two children. the victims were in two cars that collided last night on highway 50 in el dorado county near placerville. we get new information about the crash from ktvu's patti lee. >> reporter: heather, late this afternoon a chp spokesman says three people killed in the crash are from san francisco. they are presumed to be a family with one survivor, a 10- year-old girl. chp investigators are trying to determine why this prius crossed over four lanes ever highway 50 into the path of an oncoming minivan. the collision took place near placerville just after 6:00 saturday night. >> several have been flown to area hospitals, others have been ground transported and of course we have the for the fatalities. >> reporter: only one child survived. a 10-year-old girl who was seriously injured. the placerville family was in the minivan and a 4-year-old girl was killed. four others were not badly injured.